George Fisher won a scholarship from Gladstone High School to Princes. A keen footballer, Fisher played in the intercollegiate match of 1920 in the presence of HRH the Prince of Wales (later King Edward VIII). In 1921 he began studies at the University of Adelaide as a student in the engineering faculty, taking a particular interest in mining.
George Fisher joined the Zinc Corporation at Broken Hill, became underground manager and, later, general manager. In 1952 he joined Mount Isa Mines, was appointed chairman the following year and in 1972 President of MIM Holdings. He was responsible for leading the company through massive expansion and successful years until his retirement in 1973. He was also the inaugural President of the Australian Mining Industry Council. In recognition of his services to mining he was knighted in 1967.
Sir George served as the first Chancellor of James Cook University, actively participated in a wide range of community organisations and until into his nineties attended the annual PAOCA dinner in Brisbane.